Genetic fusions favor tumorigenesis through degron loss in oncogenes
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This research suggests that degron loss is a general mechanism in tumorigenesis, similar to promoter swapping, as shown in the study's PDF document . Genetic fusions favor tumorigenesis through degron loss in
Specific recurrent fusions validated included BCR-ABL, CCDC6-RET, and PML-RARA. similar to promoter swapping