ACh is released at neuromuscular junctions to stimulate skeletal muscles to contract.

Acetylcholine (ACh) is a vital chemical messenger—or neurotransmitter—that facilitates communication between neurons in both the central nervous system (brain and spinal cord) and the peripheral nervous system (nerves throughout the body). As the first neurotransmitter discovered (in 1914), it plays a crucial role in regulating muscle movement, cognitive functions, and autonomic bodily processes. Key Functions of Acetylcholine

It plays a central role in learning, memory, arousal, and attention.