Alkalating Agent -
The primary goal of these agents is to disrupt the DNA replication process. They achieve this through a process called :
: Bifunctional agents can link two DNA bases together (interstrand or intrastand cross-linking), which prevents the DNA strands from separating for replication. alkalating agent
: Repair enzymes in the cell may attempt to fix the damaged DNA, which often results in further strand breaks and fragmentation. The primary goal of these agents is to