Across these works and general usage, the phrase typically carries one of two meanings:

: A soulful track from his 2011 album Back to Love . The song describes the simple joy of spending personal time with a loved one.

The phrase "Best of Me" is a popular title used by several musical artists across different genres, ranging from soulful R&B to high-energy motivational tracks. The most prominent songs with this title include:

: An R&B hit released in 2000 from her album Fear of Flying . It reached the international charts, peaking at number 64 in Switzerland and 75 in the Netherlands.

: Often used to describe giving one's full effort, love, and "best self" to another person.

: Used to describe reaching peak performance or refusing to let the world break one's spirit.