C4.zip

A C4 ZipTip is a standard pipette tip containing a microscopic bed of resin fixed at its distal end. Unlike C18 resins, which are used for smaller peptides, the C4 resin is optimized for larger, more hydrophobic molecules like proteins and large polypeptides. Primary Uses in Research Researchers use these tools for two main reasons:

: Removing salts, buffers, and detergents that interfere with downstream analysis. For example, researchers use them to clean samples of Trastuzumab probes or mussel biotoxins before testing. c4.zip

: Best for proteins > 10 kDa and highly hydrophobic peptides. A C4 ZipTip is a standard pipette tip

Expression, Purification and Characterization of the Human ... - Nature which are used for smaller peptides

: The protein sample is aspirated through the tip, binding to the C4 resin.