Characterized by a diffuse infiltration of the splenic red pulp and a specific immunophenotype (
In cases associated with HCV infection, antiviral therapy can lead to lymphoma regression. 6. Conclusion Download Lymphomes splГ©niques pdf
Splenic lymphomas represent a heterogeneous group of rare B-cell neoplasms primarily involving the spleen, bone marrow, and often the peripheral blood. The most common subtype is Splenic Marginal Zone Lymphoma (SMZL). This paper reviews the clinical presentation, diagnostic criteria (histology and immunophenotype), and evolving therapeutic strategies for these malignancies. 1. Introduction Characterized by a diffuse infiltration of the splenic
Currently considered the first-line standard of care, offering high response rates with low toxicity. diagnostic criteria (histology and immunophenotype)
Treatment is indicated only for symptomatic patients (progressive cytopenia or painful splenomegaly).