Grey's Anatomy S16e16 Apr 2026

While the letters dominate the episode, a few other developments occur at Grey Sloan:

The central twist of the episode is that Alex has reunited with his ex-wife, . Grey's Anatomy s16e16

He expresses his gratitude for their mentorship over the years. The Big Reveal: Izzie Stevens and the Twins While the letters dominate the episode, a few

He apologizes for leaving via a letter and reveals he is filing for divorce. He leaves her his shares in Grey Sloan Memorial Hospital. He leaves her his shares in Grey Sloan Memorial Hospital

While calling former colleagues to gather support for Meredith’s medical license hearing (earlier in the season), Alex reached out to Izzie .

Alex claims that while he still loves Jo , he cannot bear to let his children grow up without a father the way he did. He is now living on a farm in Kansas where Izzie works as a surgical oncologist. ⚡ Secondary Storylines

Izzie has five-year-old twins, Eli and Alexis , who are biologically Alex’s.