Local Anesthetic 〈PRO - 2027〉

Local anesthetics are essential medications that reversibly block pain sensation in specific body parts by inhibiting the conduction of action potentials across nerve fibers. They work by blocking , preventing the influx of sodium ions required for nerve impulse generation. Chemical Classification

: This class includes procaine (Novocain), tetracaine , and benzocaine . Esters are generally less common today because they are more likely to cause allergic reactions, although procaine is noted for its low toxicity. Pharmacological Considerations Local Anesthetic Toxicity - StatPearls - NCBI Bookshelf local anesthetic

: These include commonly used agents like lidocaine , bupivacaine , articaine , mepivacaine , and prilocaine . Amides are metabolized in the liver and are the "gold standard" in modern dentistry due to their safety and lower risk of allergic reactions. Esters are generally less common today because they

Local anesthetics are categorized into two main groups based on their chemical linkage: Local anesthetics are categorized into two main groups