Pg.rar (2027)

This specific molecular feature is a critical diagnostic marker for . Key Scientific Context

, which fuses the Promyelocytic Leukemia () gene with the Retinoic Acid Receptor-alpha ( RAR ) gene.

: Depending on where the breakpoint occurs in the PML gene, three main types of fusion transcripts are formed: Long Form (L-form) : Breakpoint in PML intron 6. Short Form (S-form) : Breakpoint in PML intron 3. Variable Form (V-form) : Breakpoint in PML exon 6.

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