Use a tool like Xbox Image Browser to extract the game files from the ISO.
While many Xbox 360 and PS3 games were region-locked by manufacturers, certain titles (like Rango ) were released as "Region Free." This means a PAL (European) ISO will boot on an NTSC (North American) console without modification. Rango [Region Free][ISO]
For systems like the Xbox 360, "Region Free" ISOs are highly sought after for use with RGH (Reset Glitch Hack) or JTAG consoles, as they can be easily loaded through tools like XeXMenu or Aurora . How to Use the ISO Use a tool like Xbox Image Browser to
An ISO file is a complete "disc image" of the game's original DVD. It is typically used for preservation, emulation, or playing via hard drive on modified hardware. How to Use the ISO An ISO file