: Theodore "T-Bag" Bagwell is also in Panama, where he is seen at a hotel. His presence is a nod to the ending of The Silence of the Lambs , where a villain escapes to a tropical locale.
: Sara Tancredi realizes she is being followed and chooses to lead the authorities away from the brothers to ensure their escape, resulting in her being "in the hole" and facing significant legal danger. [S2E20] Panama
For deeper dives into the series' lore or character arcs, you can check out community discussions on the Prison Break Subreddit or detailed breakdowns on the Prison Break Wiki. Prison Break REWATCH: S2E20 - "Panama" Discussion Thread : Theodore "T-Bag" Bagwell is also in Panama,