In the Season 4 episode " Bloodline " (S4E13), Nick and Hank investigate brutal murders tied to an ancient Wesen bloodline, which fuels a dangerous, unfolding conspiracy against Portland's Wesen community. The episode, which aired on March 14, 2026, also features escalating, chaotic tensions between Adalind and Juliette as their respective powers evolve. Key moments include a breaking point in the conflict with the Wesen Council and a major, plot-shifting cliffhanger that, directed by Terrence O'Hara, sets up the next episode, "The Awakening."