: While assigned to "lumps and bumps" duty, Shane initially views the task as beneath him. However, April teaches him a valuable lesson about patient care after one of his routine procedures leads to an early cancer detection, ultimately earning him a spot on a major surgery with Callie. The Ending Note
Watch the closing moments of the episode as the interns reflect on their future in medicine: [S9E8] Love Turns You Upside Down
: Meredith enlists Heather Brooks to contact Derek's sisters to find a donor nerve for his hand surgery. Heather eventually stands up to both Derek and Meredith after being caught in the middle of their family drama, leading to the arrival of Derek's sister, Lizzie Shepherd (played by Neve Campbell). : While assigned to "lumps and bumps" duty,
: Cristina Yang pits interns Stephanie Edwards and Leah Murphy against each other in a fierce competition for OR time. Their extreme competitiveness nearly leads to a medical disaster for a heart transplant patient, resulting in them being temporarily banned from the OR. Heather eventually stands up to both Derek and
The episode concludes with the interns watching the senior doctors in a moment of organized chaos in the ER. Realizing the weight of the profession, Jo Wilson voices a sentiment that echoes the episode's theme of growth and change: "".
: Alex nicknames Jo "Princess," assuming she comes from a privileged background. After working together to save a baby's life in the NICU, Jo reveals her difficult past—being abandoned as a baby and living in her car during high school—which causes Alex to see her in a new, more respectful light.