Transferase · Free Access
A−X+B→A+B−Xcap A minus cap X plus cap B right arrow cap A plus cap B minus cap X is the donor, is the functional group, and is the acceptor. Primary Subclasses
Transferases are found throughout the cell, with high concentrations in the cytosol, mitochondria, and Golgi bodies. Molecule of the Month: Glutathione Transferases - PDB-101 transferase
), critical for DNA methylation and gene expression regulation. A−X+B→A+B−Xcap A minus cap X plus cap B
: Transfer phosphate groups (typically from ATP) to substrates, a process essential for cell signaling and metabolic regulation. Aminotransferases (EC 2.6) : Transfer amino groups ( −NH2negative cap N cap H sub 2 : Transfer phosphate groups (typically from ATP) to
: Transfer acyl groups, vital for fatty acid metabolism and the synthesis of structured lipids. Biological Roles
: Transfer sugar moieties to form glycosidic bonds, which are essential for synthesizing blood group antigens and modifying drug stability.